Thursday, November 17, 2011

Magnesium Sulfate (quick refresher)

ECCLAMPSIA:
--dose: 4-6 grams IV over 15 min, 1-2 g/hour infusion s/p

ASTHMA:
--dose: 2 grams IV over 15 min

TORSADES:
--dose: 1-2 grams IV over 15 min (or faster, if coding)
--peds dose: 25-75mg/kg

POSSIBLE SIDE EFFECTS:
--heart block (slows SA node impulse & prolongs conduction time)
--hyporeflexia
--respiratory depression
--CNS depression
--vasodilation/flushing/hypotension (rate related)

10-SECOND VERSION:
--magnesium sulfate, worth a shot in ecclampsia, torsades, refractory asthma, refractory death (ACLS option), hypomag
--dosing: 2 g IV for most (25-75mg/kg up to 2g max for kids), a little more for (4-6 g) for seizing patients, best if over 15 minutes
--test/pimping question: side effects/toxicity indicated by resp/CNS depression, hyporeflexia

Reference(s): http://www.uptodate.com/

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